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Tg(tetO-Grm1)7Atai
Transgene Detail
Summary
Symbol: Tg(tetO-Grm1)7Atai
Name: transgene insertion 7, Atsu Aiba
MGI ID: MGI:3715306
Synonyms: Tg(TRE-Grm1)7Atai, TRE-mGluR1a
Transgene: Tg(tetO-Grm1)7Atai  Location: unknown  
Alliance: Tg(tetO-Grm1)7Atai page
Transgene
origin
Strain of Origin:  C57BL/6N
Transgene
description
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Mutation detailsA tetracycline responsive element (TRE), which consists of heptamerized tet operator (tetO) sequences, the binding sites of TetR, located upstream of a cytomegalovirus minimal promoter was fused to the rat Grm1 open reading frame. Grm1 is expressed upon binding of the tetracycline-controlled transactivator (tTA) protein to the promoter. (J:122536)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:122536 Nakao H, et al., Metabotropic glutamate receptor subtype-1 is essential for motor coordination in the adult cerebellum. Neurosci Res. 2007 Apr;57(4):538-43
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory