Pcp2^{tm1(tTA)23Atai}
Targeted Allele Detail

Summary

• Symbol: Pcp2^{tm1(tTA)23Atai}
• Name: Purkinje cell protein 2 (L7); targeted mutation 23, Atsu Aiba
• MGI ID: MGI:3715310
• Synonyms: L7-tTA
• Gene: Pcp2 Location: Chr8:3673371-3675545 bp, - strand Genetic Position: Chr8, 1.92 cM
• Alliance: Pcp2^{tm1(tTA)23Atai} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122536
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Transactivator)
• Mutation: Insertion
• Mutation details: 1.0kb of the tetracycline-controlled transactivator (tTA) cDNA fragment from the pTet-Off was inserted into exon 4. (J:122536)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pcp2 Mutation: 35 strains or lines available

Notes

This construct was injected into Grm1^tm1Stl embryos along with Tg

References

• Original: J:122536 Nakao H, et al., Metabotropic glutamate receptor subtype-1 is essential for motor coordination in the adult cerebellum. Neurosci Res. 2007 Apr;57(4):538-43
• All: 4 reference(s)