Tg(Tnni3-cre/GFP)1Mknn
Transgene Detail

Summary

• Symbol: Tg(Tnni3-cre/GFP)1Mknn
• Name: transgene insertion 1, Michael Koenen
• MGI ID: MGI:3715463
• Synonyms: cTnI-Cre-GFP
• Transgene: Tg(Tnni3-cre/GFP)1Mknn Location: unknown
• Alliance: Tg(Tnni3-cre/GFP)1Mknn page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F2

Transgene description

• Transgene Type: Transgenic (Recombinase, Reporter)
• Mutation: Insertion
• Tg(Tnni3-cre/GFP)1Mknn expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Tnni3

• Mutation details: A 4.3kb promoter fragment was placed upstream of a cre-GFP cassette. The transgene drives expression in the heart at E16.5 that rises slowly durng fetal development and increased neonatally. Expression at day 30 is in the ventricular and artrial myocytes with no recombination occuring in other tissues. (J:122464)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tnni3 (species not specified) Summary of all recombinase alleles driven by Tnni3. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:122464 Opherk JP, et al., Cardiac-specific activation of Cre expression at late fetal development. Biochem Biophys Res Commun. 2007 Jul 27;359(2):209-213
• All: 1 reference(s)