Cmah^tm1Avrk
Targeted Allele Detail

Summary

• Symbol: Cmah^tm1Avrk
• Name: cytidine monophospho-N-acetylneuraminic acid hydroxylase; targeted mutation 1, Ajit Varki
• MGI ID: MGI:3715527
• Synonyms: Cmah^-
• Gene: Cmah Location: Chr13:24511387-24661272 bp, + strand Genetic Position: Chr13, 10.34 cM, cytoband A3.2
• Alliance: Cmah^tm1Avrk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122351
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exon 6 and a floxed TK/neo were removed via transient cre mediated recombination. (J:122351)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 5 strains available Cell Lines: 0 lines available
• Carrying any Cmah Mutation: 37 strains or lines available

References

• Original: J:122351 Hedlund M, et al., N-glycolylneuraminic acid deficiency in mice: implications for human biology and evolution. Mol Cell Biol. 2007 Jun;27(12):4340-6
• All: 28 reference(s)