Tg(282M13)1Kng
Transgene Detail

Summary

• Symbol: Tg(282M13)1Kng
• Name: transgene insertion 1, David M Kingsley
• MGI ID: MGI:3715532
• Synonyms: BAC C
• Transgene: Tg(282M13)1Kng Location: unknown
• Alliance: Tg(282M13)1Kng page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(282M13)1Kng expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ank (MGI:3045421)

• Mutation details: An approximately 450kb BAC fragment within the larger region flanked by markers D15Mit251 and D15Mit155 was used to create a transgene that could rescue the phenotype of the homozygous Ank^Ank mouse. The BAC fragment contains 11 EST clusters, including the Ank gene. (J:63420)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Founder mice were crossed to C3FeB6 A/A-Ank^ank/J mice and their offspring intercrossed to observe whether the Ank^ank phenotype was rescued in Ank^ank/Ank^ank F2 progeny carrying the transgene.

References

• Original: J:63420 Ho AM, et al., Role of the mouse ank gene in control of tissue calcification and arthritis [see comments]. Science. 2000 Jul 14;289(5477):265-70
• All: 2 reference(s)