Del(6Hoxa)1Ddu
Targeted Allele Detail

Summary

• Symbol: Del(6Hoxa)1Ddu
• Name: deletion, Chr 6, Denis Duboule 1
• MGI ID: MGI:3715855
• Synonyms: Del1Ddu, Hoxa^-, Hoxa^delneo, HoxAdelneo, Hoxa^tm1.1Ddu
• Gene: Del(6Hoxa)1Ddu Location: unknown Genetic Position: Chr6, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:99350
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intergenic deletion
• Del(6Hoxa)1Ddu involves 32 genes/genome features (Gm27454, Gm27477, Gm27492 ...) View all
• Mutation details: Mice heterozygous for the Hoxa^tm1Ddu allele were crossed with mice carrying the Tg(Prrx1-cre)1Cjt transgene to delete the floxed Hoxa1-Hoxa13 gene cluster. (J:99350)

Expression

In Mice Carrying this Mutation:

22 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(6Hoxa)1Ddu Mutation: 0 strains or lines available

References

• Original: J:99350 Kmita M, et al., Early developmental arrest of mammalian limbs lacking HoxA/HoxD gene function. Nature. 2005 Jun 23;435(7045):1113-6
• All: 8 reference(s)