Inpp5d^tm1Rav
Targeted Allele Detail

Summary

• Symbol: Inpp5d^tm1Rav
• Name: inositol polyphosphate-5-phosphatase D; targeted mutation 1, Jeffrey V Ravetch
• MGI ID: MGI:3715982
• Synonyms: Ship^fl, Ship^flox
• Gene: Inpp5d Location: Chr1:87548034-87648229 bp, + strand Genetic Position: Chr1, 44.44 cM, cytoband C5
• Alliance: Inpp5d^tm1Rav page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:119256
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• LoxP sites were inserted to flank exons 10 and 11. (J:119256)

Disease models

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Inpp5d Mutation: 94 strains or lines available

References

• Original: J:119256 Karlsson MC, et al., Macrophages control the retention and trafficking of B lymphocytes in the splenic marginal zone. J Exp Med. 2003 Jul 21;198(2):333-40
• All: 14 reference(s)