Tmem38b^tm1Hta
Targeted Allele Detail

Summary

• Symbol: Tmem38b^tm1Hta
• Name: transmembrane protein 38B; targeted mutation 1, Hiroshi Takeshima
• MGI ID: MGI:3716065
• Synonyms: Tric-b^-
• Gene: Tmem38b Location: Chr4:53826045-53862019 bp, + strand Genetic Position: Chr4, 28.76 cM
• Alliance: Tmem38b^tm1Hta page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122817
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A neomycin resistance gene was inserted into exon 1. Absence of transcript and protein was confirmed in mutant heart samples. (J:122817)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmem38b Mutation: 54 strains or lines available

References

• Original: J:122817 Yazawa M, et al., TRIC channels are essential for Ca2+ handling in intracellular stores. Nature. 2007 Jul 5;448(7149):78-82
• All: 5 reference(s)