Bsx^tm1Tre
Targeted Allele Detail

Summary

• Symbol: Bsx^tm1Tre
• Name: brain specific homeobox; targeted mutation 1, Mathias Treier
• MGI ID: MGI:3716209
• Synonyms: Bsx^HD
• Gene: Bsx Location: Chr9:40785423-40791353 bp, + strand Genetic Position: Chr9, 21.65 cM
• Alliance: Bsx^tm1Tre page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122746
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The lacZ coding sequence was inserted with a neomycin resistance cassette in frame, thereby deleting part of exon 2. This exon encodes helix 1 and 2 of the homeodomain. (J:122746)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bsx Mutation: 19 strains or lines available

References

• Original: J:122746 Sakkou M, et al., A role for brain-specific homeobox factor bsx in the control of hyperphagia and locomotory behavior. Cell Metab. 2007 Jun;5(6):450-63
• All: 1 reference(s)