Magi2^tm1Yhat
Targeted Allele Detail

Summary

• Symbol: Magi2^tm1Yhat
• Name: membrane associated guanylate kinase, WW and PDZ domain containing 2; targeted mutation 1, Yutaka Hata
• MGI ID: MGI:3716218
• Synonyms: S-scamalpha^-
• Gene: Magi2 Location: Chr5:19432034-20909790 bp, + strand Genetic Position: Chr5, 8.6 cM, cytoband A3
• Alliance: Magi2^tm1Yhat page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122354
• Parent Cell Line: CCE/EK.CCE (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 1 was replaced by a neomycin resistance cassette to delete only the alpha isoform. (J:122354)

Expression

In Mice Carrying this Mutation:

15 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Magi2 Mutation: 72 strains or lines available

References

• Original: J:122354 Iida J, et al., Synaptic scaffolding molecule alpha is a scaffold to mediate N-methyl-D-aspartate receptor-dependent RhoA activation in dendrites. Mol Cell Biol. 2007 Jun;27(12):4388-405
• All: 2 reference(s)