Tg(Ckm*-Mstn)1Nfg
Transgene Detail

Summary

• Symbol: Tg(Ckm*-Mstn)1Nfg
• Name: transgene insertion 1, Nestor F Gonzales-Cadavid
• MGI ID: MGI:3716428
• Synonyms: MCK-3E/Ms, MCK-3E/Mst
• Transgene: Tg(Ckm*-Mstn)1Nfg Location: unknown
• Alliance: Tg(Ckm*-Mstn)1Nfg page

Transgene origin

• Strain of Origin: (BALB/c x C57BL/6)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Ckm*-Mstn)1Nfg expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Mstn (MGI:95691)

• Mutation details: This transgene consists of the full-length mouse myostatin cDNA under the control of a mutated muscle creatine kinase promotor. The promotor contains a triple mutation in the E-boxes and abolishes expression in cardiac muscle, thus Mstn is only expressed in skeletal muscle. (J:123052)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:123052 Reisz-Porszasz S, et al., Lower skeletal muscle mass in male transgenic mice with muscle-specific overexpression of myostatin. Am J Physiol Endocrinol Metab. 2003 Oct;285(4):E876-88
• All: 2 reference(s)