Scx^tm1Stzr
Targeted Allele Detail

Summary

• Symbol: Scx^tm1Stzr
• Name: scleraxis scleraxis bHLH transcription factor; targeted mutation 1, Ronen Schweitzer
• MGI ID: MGI:3716563
• Synonyms: Scx^flox
• Gene: Scx Location: Chr15:76341652-76343658 bp, + strand Genetic Position: Chr15, 35.92 cM
• Alliance: Scx^tm1Stzr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122742
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to insert loxP sites to flank part of the 5' UTR, exon 1 and a Frt-flanked neo cassette. Crossing with FLP deleter mice removed the neo. (J:122742)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Scx Mutation: 15 strains or lines available

References

• Original: J:122742 Murchison ND, et al., Regulation of tendon differentiation by scleraxis distinguishes force-transmitting tendons from muscle-anchoring tendons. Development. 2007 Jul;134(14):2697-708
• All: 7 reference(s)