Ntrk2^tm2Lfr
Targeted Allele Detail

Summary

• Symbol: Ntrk2^tm2Lfr
• Name: neurotrophic tyrosine kinase, receptor, type 2; targeted mutation 2, Louis F Reichardt
• MGI ID: MGI:3716645
• Synonyms: TrkB^f
• Gene: Ntrk2 Location: Chr13:58954383-59281784 bp, + strand Genetic Position: Chr13, 31.2 cM
• Alliance: Ntrk2^tm2Lfr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122929
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The first exon is surrounded by loxP sites. An FRT-flanked neo cassette was removed by flp-mediated recombination. (J:168326)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ntrk2 Mutation: 66 strains or lines available

References

• Original: J:122929 Liu X, et al., Brain-derived neurotrophic factor and TrkB modulate visual experience-dependent refinement of neuronal pathways in retina. J Neurosci. 2007 Jul 4;27(27):7256-67
• All: 17 reference(s)