Shc1^tm8Paw
Targeted Allele Detail

Summary

• Symbol: Shc1^tm8Paw
• Name: src homology 2 domain-containing transforming protein C1; targeted mutation 8, Tony Pawson
• MGI ID: MGI:3716782
• Synonyms: Shca^flxbeta
• Gene: Shc1 Location: Chr3:89325858-89337336 bp, + strand Genetic Position: Chr3, 39.11 cM
• Alliance: Shc1^tm8Paw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122927
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A floxed splice acceptor-IRES-betageo-polyA cassette was inserted into intron 4. (J:122927)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Shc1 Mutation: 66 strains or lines available

References

• Original: J:122927 Hardy WR, et al., Combinatorial ShcA docking interactions support diversity in tissue morphogenesis. Science. 2007 Jul 13;317(5835):251-6
• All: 1 reference(s)