Tg(ACTB-tTS)1Mllo
Transgene Detail
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| Symbol: |
Tg(ACTB-tTS)1Mllo |
| Name: |
transgene insertion 1, Moises Mallo |
| MGI ID: |
MGI:3717162 |
| Synonyms: |
beta-actin-tTS, beta-act-tTS |
| Transgene: |
Tg(ACTB-tTS)1Mllo Location: unknown
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| Alliance: |
Tg(ACTB-tTS)1Mllo page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: The transgene contains the human beta actin promoter upstream of a chimeric gene encoding an enhanced tetracycline regulated repressor protein (tTS) that comprises the C-terminal portion of the E. coli Tn10 tetracycline repressor (TetR) protein, the 6-amino acid SV40 large T-antigen nuclear localization signal and the N-terminal 121 amino acids of the human ZNF10 (KOX1) zinc finger protein, which contains the KRAB repressor domain, followed by an SV40 polyadenylation signal. The expression construct is flanked by chicken beta-globin insulators.
(J:82970)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 2 strains available
Cell Lines: 0 lines available
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| Original: |
J:82970 Mallo M, et al., Reversible gene inactivation in the mouse. Genomics. 2003 Apr;81(4):356-60 |
| All: |
12 reference(s) |
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Analysis Tools
