Cdc25a^tm1Kiyo
Targeted Allele Detail

Summary

• Symbol: Cdc25a^tm1Kiyo
• Name: cell division cycle 25A; targeted mutation 1, Hiroaki Kiyokawa
• MGI ID: MGI:3717591
• Synonyms: Cdc25a^-
• Gene: Cdc25a Location: Chr9:109704647-109722963 bp, + strand Genetic Position: Chr9, 59.81 cM
• Alliance: Cdc25a^tm1Kiyo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:123144
• Parent Cell Line: GS1 (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 7-9 were replaced by a neomycin resistance cassette. (J:123144)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdc25a Mutation: 34 strains or lines available

References

• Original: J:123144 Ray D, et al., Hemizygous disruption of Cdc25A inhibits cellular transformation and mammary tumorigenesis in mice. Cancer Res. 2007 Jul 15;67(14):6605-11
• All: 4 reference(s)