Tg(SOD1)51Yg
Transgene Detail

Summary

• Symbol: Tg(SOD1)51Yg
• Name: transgene insertion 51, Yoram Groner
• MGI ID: MGI:3718455
• Synonyms: tg-SOD69
• Transgene: Tg(SOD1)51Yg Location: unknown
• Alliance: Tg(SOD1)51Yg page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(SOD1)51Yg expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SOD1 (6647)

  Sod1	(MGI:98351)

• Mutation details: A 14.5 kb fragment of human genomic DNA containing the entire SOD1 gene, including its regulatory sequences, was used for microinjection into fertilized eggs. Line 51 contains 4-5 copies of the transgene and expresses 3-5-fold more superoxide dismutase 1in the brain than non-transgenic mice. (J:96742)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:96742 Harris-Cerruti C, et al., Functional and morphological alterations in compound transgenic mice overexpressing Cu/Zn superoxide dismutase and amyloid precursor protein [correction]. Eur J Neurosci. 2004 Mar;19(5):1174-90
• All: 1 reference(s)