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Tg(Wnt1-En1)1Amc
Transgene Detail
Summary
Symbol: Tg(Wnt1-En1)1Amc
Name: transgene insertion 1, Andrew P McMahon
MGI ID: MGI:3718490
Synonyms: WEXPZ-En-1
Transgene: Tg(Wnt1-En1)1Amc  Location: unknown  
Alliance: Tg(Wnt1-En1)1Amc page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Wnt1-En1)1Amc expresses 1 gene
 
Mutation detailsAn En1 cDNA and an 825 base-pair piece of the E. Coli lacZ were inserted in the EcoRV site of the pWEXP2 plasmnid. This plasmid contains a Wnt1 genomic fragment which has been modified in such a way that the Wnt1 translation initiation codon has been replaced with a polylinker containing NruI, EcoRV, SacII, and BstBI restriction sites. (J:16386, J:35491)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:35491 Danielian PS, et al., Engrailed-1 as a target of the Wnt-1 signalling pathway in vertebrate midbrain development. Nature. 1996 Sep 26;383(6598):332-4
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory