Tg(Wnt1-En1)1Amc
Transgene Detail

Summary

• Symbol: Tg(Wnt1-En1)1Amc
• Name: transgene insertion 1, Andrew P McMahon
• MGI ID: MGI:3718490
• Synonyms: WEXPZ-En-1
• Transgene: Tg(Wnt1-En1)1Amc Location: unknown
• Alliance: Tg(Wnt1-En1)1Amc page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Wnt1-En1)1Amc expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	En1 (MGI:95389)

• Mutation details: An En1 cDNA and an 825 base-pair piece of the E. Coli lacZ were inserted in the EcoRV site of the pWEXP2 plasmnid. This plasmid contains a Wnt1 genomic fragment which has been modified in such a way that the Wnt1 translation initiation codon has been replaced with a polylinker containing NruI, EcoRV, SacII, and BstBI restriction sites. (J:16386, J:35491)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:35491 Danielian PS, et al., Engrailed-1 as a target of the Wnt-1 signalling pathway in vertebrate midbrain development. Nature. 1996 Sep 26;383(6598):332-4
• All: 5 reference(s)