Ramp3^tm1Kmca
Targeted Allele Detail

Summary

• Symbol: Ramp3^tm1Kmca
• Name: receptor (calcitonin) activity modifying protein 3; targeted mutation 1, Kathleen Caron
• MGI ID: MGI:3718499
• Synonyms: Ramp3^-
• Gene: Ramp3 Location: Chr11:6608521-6627475 bp, + strand Genetic Position: Chr11, 4.61 cM
• Alliance: Ramp3^tm1Kmca page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:123382
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 and 3 were replaced with the neomycin resistance cassette. Quantitative RT-PCR did not detect transcripts in mutant embryonic RNA extracts. (J:123382)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ramp3 Mutation: 18 strains or lines available

References

• Original: J:123382 Dackor R, et al., Receptor activity-modifying proteins 2 and 3 have distinct physiological functions from embryogenesis to old age. J Biol Chem. 2007 Jun 22;282(25):18094-9
• All: 5 reference(s)