Ubr3^tm1Ytkw
Targeted Allele Detail

Summary

• Symbol: Ubr3^tm1Ytkw
• Name: ubiquitin protein ligase E3 component n-recognin 3; targeted mutation 1, Yong Tae Kwon
• MGI ID: MGI:3718505
• Synonyms: Ubr3^-, Ubr3^nlsLacZ
• Gene: Ubr3 Location: Chr2:69727590-69854357 bp, + strand Genetic Position: Chr2, 40.95 cM
• Alliance: Ubr3^tm1Ytkw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:123383
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced by an nls-lacZ cassette and a floxed neomycin resistance gene. Absence of transcript was confirmed by Northern blot. (J:123383)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ubr3 Mutation: 121 strains or lines available

References

• Original: J:123383 Tasaki T, et al., Biochemical and genetic studies of UBR3, a ubiquitin ligase with a function in olfactory and other sensory systems. J Biol Chem. 2007 Jun 22;282(25):18510-20
• All: 1 reference(s)