Adgrv1^tm2Msat
Targeted Allele Detail

Summary

• Symbol: Adgrv1^tm2Msat
• Name: adhesion G protein-coupled receptor V1; targeted mutation 2, Makoto Sato
• MGI ID: MGI:3718538
• Synonyms: Vlgr1-EYFP
• Gene: Adgrv1 Location: Chr13:81243187-81781273 bp, - strand Genetic Position: Chr13, 42.18 cM
• Alliance: Adgrv1^tm2Msat page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:123389
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A vector was designed to insert an enhanced yellow fluorescent protein and a PGK-neo in frame, following the first 20 bp of exon 2. The rest of exon 2 and all of exons 3 and 4 were deleted. (J:123389)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Adgrv1 Mutation: 318 strains or lines available

References

• Original: J:123389 Yagi H, et al., Vlgr1 is required for proper stereocilia maturation of cochlear hair cells. Genes Cells. 2007 Feb;12(2):235-50
• All: 1 reference(s)