Gmnn^tm1Nyma
Targeted Allele Detail

Summary

• Symbol: Gmnn^tm1Nyma
• Name: geminin; targeted mutation 1, Keiko Nakayama
• MGI ID: MGI:3718544
• Gene: Gmnn Location: Chr13:24935828-24945906 bp, - strand Genetic Position: Chr13, 10.64 cM
• Alliance: Gmnn^tm1Nyma page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:123394
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 5 and 6, which encode the coiled-coil domain, were replaced a PGK-neo-polyA. (J:123394)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gmnn Mutation: 27 strains or lines available

References

• Original: J:123394 Hara K, et al., Geminin is essential for the development of preimplantation mouse embryos. Genes Cells. 2006 Nov;11(11):1281-93
• All: 1 reference(s)