Creb3l4^tm1Noj
Targeted Allele Detail

Summary

• Symbol: Creb3l4^tm1Noj
• Name: cAMP responsive element binding protein 3-like 4; targeted mutation 1, Hiroshi Nojima
• MGI ID: MGI:3718553
• Synonyms: Tisp40^-
• Gene: Creb3l4 Location: Chr3:90144807-90150819 bp, - strand Genetic Position: Chr3, 39.21 cM
• Alliance: Creb3l4^tm1Noj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:123396
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 5-10, which encode the basic zipper and transmembrane regions, were replaced by a neomycin resistance cassette. Absence of transcript was confirmed by Northern blot analysis. (J:123396)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Creb3l4 Mutation: 23 strains or lines available

References

• Original: J:123396 Nagamori I, et al., The testes-specific bZip type transcription factor Tisp40 plays a role in ER stress responses and chromatin packaging during spermiogenesis. Genes Cells. 2006 Oct;11(10):1161-71
• All: 7 reference(s)