En1^{tm3.1(En2)Alj}
Targeted Allele Detail

Summary

• Symbol: En1^{tm3.1(En2)Alj}
• Name: engrailed 1; targeted mutation 3.1, Alexandra Joyner
• MGI ID: MGI:3718978
• Gene: En1 Location: Chr1:120530246-120535719 bp, + strand Genetic Position: Chr1, 52.74 cM, cytoband C2-qter
• Alliance: En1^{tm3.1(En2)Alj} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:50311
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Null/knockout)
• Mutation: Insertion
• This allele was derived from En1^tm3(En2)Alj by excision of the floxed neo cassette. (J:50311)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any En1 Mutation: 34 strains or lines available

References

• Original: J:50311 Hanks MC, et al., Drosophila engrailed can substitute for mouse Engrailed1 function in mid-hindbrain, but not limb development. Development. 1998 Nov;125(22):4521-30
• All: 1 reference(s)