Bcl6btm2Dent
Targeted Allele Detail
|
Symbol: |
Bcl6btm2Dent |
Name: |
B cell CLL/lymphoma 6, member B; targeted mutation 2, Alexander Dent |
MGI ID: |
MGI:3719094 |
Synonyms: |
Bazf- |
Gene: |
Bcl6b Location: Chr11:70114954-70120624 bp, - strand Genetic Position: Chr11, 42.99 cM, cytoband B4
|
Alliance: |
Bcl6btm2Dent page
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:123621
|
Parent Cell Line: |
Not Specified (ES Cell)
|
Strain of Origin: |
Not Specified
|
|
Allele Type: |
|
Targeted (Null/knockout) |
Mutations: |
|
Insertion, Intragenic deletion
|
|
|
Mutation details: A region encoding 124 C-terminal amino acids was replaced by a pgk-neo cassette. This deleted region contained all of the zinc finger amino acids, and thus the targeted gene was rendered incapable of producing a DNA binding protein by alternative splicing. RT-PCR confirmed absence of transcript from mutant lungs.
(J:123621)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Bcl6b Mutation: |
16 strains or lines available
|
|
Original: |
J:123621 Broxmeyer HE, et al., Aberrant regulation of hematopoiesis by T cells in BAZF-deficient mice. Mol Cell Biol. 2007 Aug;27(15):5275-85 |
All: |
1 reference(s) |
|