Trip13^{Gt(RRB047)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Trip13^{Gt(RRB047)Byg}
• Name: thyroid hormone receptor interactor 13; gene trap RRB047, BayGenomics
• MGI ID: MGI:3719273
• Synonyms: Pch2^TRIP13, Trip13^Gt, Trip13^mod
• Gene: Trip13 Location: Chr13:74060577-74085855 bp, - strand Genetic Position: Chr13, 40.15 cM, cytoband C1
• Alliance: Trip13^{Gt(RRB047)Byg} page

Developmental histology of Trip13^{Gt(RRB047)Byg}/Trip13^{Gt(RRB047)Byg} mouse testes

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: RRB047
• Germline Transmission: Earliest citation of germline transmission: J:123677
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1Lxf Vector Type: gene trap
• Mutation details: The insertion of the gene trap into intron 3 resulted in a fusion transcript of exons 1-3 and the betageo gene. (J:123677)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  RRB047	CC183268 ; (MGI Seq Detail)	5' RACE	Chr13:74080979-74085726 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  13 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:	5 assay results
In Structures Affected by this Mutation:	7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trip13 Mutation: 34 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:123677 Li X, et al., Mouse Pachytene Checkpoint 2 (Trip13) Is Required for Completing Meiotic Recombination but Not Synapsis. PLoS Genet. 2007 Aug 10;3(8):e130
• All: 11 reference(s)