Enpp2^tm1.1Bout
Targeted Allele Detail

Summary

• Symbol: Enpp2^tm1.1Bout
• Name: ectonucleotide pyrophosphatase/phosphodiesterase 2; targeted mutation 1.1, Jean A Boutin
• MGI ID: MGI:3720192
• Synonyms: Atx^-
• Gene: Enpp2 Location: Chr15:54702297-54816284 bp, - strand Genetic Position: Chr15, 21.6 cM, cytoband D2
• Alliance: Enpp2^tm1.1Bout page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:123726
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Single point mutation
• Cre mediated excision removed the floxed neo, leaving the T210A transversion in exon 7. (J:123726)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Enpp2 Mutation: 79 strains or lines available

References

• Original: J:123726 Ferry G, et al., Functional invalidation of the autotaxin gene by a single amino acid mutation in mouse is lethal. FEBS Lett. 2007 Jul 24;581(18):3572-8
• All: 1 reference(s)