About   Help   FAQ
Mapttm1Aha
Targeted Allele Detail
Summary
Symbol: Mapttm1Aha
Name: microtubule-associated protein tau; targeted mutation 1, Akihiro Harada
MGI ID: MGI:3720198
Synonyms: tau-
Gene: Mapt  Location: Chr11:104122216-104222916 bp, + strand  Genetic Position: Chr11, 67.79 cM, cytoband E1
Alliance: Mapttm1Aha page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:123734
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAn frt-flanked pgk-neo was inserted to replace exon 1 in reverse orientation. Western blot confirmed absence of transcript in mutant brain samples. (J:123734)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mapt Mutation:  430 strains or lines available
References
Original:  J:123734 Fujio K, et al., 14-3-3 proteins and protein phosphatases are not reduced in tau-deficient mice. Neuroreport. 2007 Jul 2;18(10):1049-52
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory