Gata3^tm1.2Mbu
Targeted Allele Detail

Summary

• Symbol: Gata3^tm1.2Mbu
• Name: GATA binding protein 3; targeted mutation 1.2, Meinrad Busslinger
• MGI ID: MGI:3720332
• Synonyms: Gata3^GFP, Gata3^tm1.2Bchd
• Gene: Gata3 Location: Chr2:9861889-9894845 bp, - strand Genetic Position: Chr2, 6.69 cM
• Alliance: Gata3^tm1.2Mbu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:104408
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exon 4 is removed by Cre-mediated recombination. (J:104408)

Expression

In Mice Carrying this Mutation:	9 assay results 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gata3 Mutation: 32 strains or lines available

References

• Original: J:104408 Grote D, et al., Pax2/8-regulated Gata3 expression is necessary for morphogenesis and guidance of the nephric duct in the developing kidney. Development. 2006 Jan;133(1):53-61
• All: 9 reference(s)