Aicda^tm1(cre)Mnz
Targeted Allele Detail

Summary

• Symbol: Aicda^tm1(cre)Mnz
• Name: activation-induced cytidine deaminase; targeted mutation 1, Michel C Nussenzweig
• MGI ID: MGI:3720568
• Synonyms: AID^-, AID Cre, AID^Cre
• Gene: Aicda Location: Chr6:122530768-122541139 bp, + strand Genetic Position: Chr6, 57.65 cM, cytoband F2
• Alliance: Aicda^tm1(cre)Mnz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:153206
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Aicda^tm1(cre)Mnz expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Aicda (MGI:1342279)

• Mutation details: A targeting vector containing Cre, an FRT-flanked neomycin resistance cassette, and a DTA (diphtheria toxin) gene was used to replace exon 1 of the gene. (J:145691, J:153206)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Aicda (mouse) Summary of all recombinase alleles driven by Aicda. Alliance mouse Aicda gene page

Tumor Data

List all tumor models in MMHCdb carrying Aicda^tm1(cre)Mnz

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Aicda Mutation: 57 strains or lines available

References

• Original: J:153206 Nussenzweig MC, Generation of an Aicda knock-in cre allele. MGI Direct Data Submission. 2009
• All: 52 reference(s)