Tg(Itgax-cre,-EGFP)4097Ach
Transgene Detail

Summary

• Symbol: Tg(Itgax-cre,-EGFP)4097Ach
• Name: transgene insertion 4097, Alexander V Chervonsky
• MGI ID: MGI:3720729
• Synonyms: CD11c-Cre, CD11c-Cre 4907, CD11c-Cre-GFP, CD11c-Cre-GFP.4097, Tg(Itgax-cre,EGFP)4097Ach
• Transgene: Tg(Itgax-cre,-EGFP)4097Ach Location: unknown
• Alliance: Tg(Itgax-cre,-EGFP)4097Ach page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Itgax-cre,-EGFP)4097Ach expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Itgax

• Mutation details: The Itgax promoter and enchancer were used to drive cre expression in a pIRES2-EGFP-based plasmid. Two lines were created with line 4097 exhibiting greater expression than 4272 in dendritic cells. (J:123556)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Itgax (species not specified) Summary of all recombinase alleles driven by Itgax.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 5 strains available Cell Lines: 0 lines available

Notes

Two lines were created with line 4097 exhibiting greater expression than 4272 in dendritic cells.

References

• Original: J:123556 Stranges PB, et al., Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity. Immunity. 2007 May;26(5):629-41
• All: 93 reference(s)