Ophn1^Wtgr
Spontaneous Allele Detail

Summary

• Symbol: Ophn1^Wtgr
• Name: oligophrenin 1; wavy tiger
• MGI ID: MGI:3720821
• Gene: Ophn1 Location: ChrX:97597883-97934631 bp, - strand Genetic Position: ChrX, 42.94 cM, cytoband C2
• Alliance: Ophn1^Wtgr page

Mutation origin

• Strain of Origin: DBA/2J

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: An A-to-C point mutation at coding nucleotide 1639 of the cDNA (NM_052976) results in a lysine to glutamine substitution at position 547 of the encoded protein (p.K547Q). (J:222308)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ophn1 Mutation: 12 strains or lines available

References

• Original: J:123336 Giggey J, et al., A new X-linked Dominant Mutation called Wavy Tiger. MGI Direct Data Submission. 2007
• All: 2 reference(s)