Cdk5^tm1Bibb
Targeted Allele Detail

Summary

• Symbol: Cdk5^tm1Bibb
• Name: cyclin dependent kinase 5; targeted mutation 1, James A Bibb
• MGI ID: MGI:3720892
• Synonyms: fCDK5
• Gene: Cdk5 Location: Chr5:24623239-24628528 bp, - strand Genetic Position: Chr5, 11.73 cM, cytoband A3-B1
• Alliance: Cdk5^tm1Bibb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:124046
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted to flank exons 2-5, the exons encoding the vital catalytic-domain components. (J:124046)

Expression

In Mice Carrying this Mutation:

12 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdk5 Mutation: 17 strains or lines available

References

• Original: J:124046 Hawasli AH, et al., Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation. Nat Neurosci. 2007 Jul;10(7):880-6
• All: 18 reference(s)