Tg(Prnp-cre/ERT)28.4Ics
Transgene Detail

Summary

• Symbol: Tg(Prnp-cre/ERT)28.4Ics
• Name: transgene insertion 28.4, Mouse Clinical Institute
• MGI ID: MGI:3720937
• Synonyms: Cre-ER^T, PrP-Cre-ER^T, PrP-Cre-ERT(28.4), Tg(Prnp-cre/Esr1)28.4Ics
• Transgene: Tg(Prnp-cre/ERT)28.4Ics Location: unknown
• Alliance: Tg(Prnp-cre/ERT)28.4Ics page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F1

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Prnp-cre/ERT)28.4Ics expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Prnp (MGI:97769)

• Mutation details: The mouse prion promoter was used to drive the expression of the tamoxifen-inducible form of a Cre recombinase/estrogen receptor fusion protein. Ten lines were obtained with 28.6 and 28.8 also analyzed. (J:81569)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Prnp (mouse) Summary of all recombinase alleles driven by Prnp. Comparative matrix view of recombinase activities Alliance mouse Prnp gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:81569 Weber P, et al., Temporally controlled targeted somatic mutagenesis in the mouse brain. Eur J Neurosci. 2001 Dec;14(11):1777-83
• All: 11 reference(s)