Wt1^tm1Nhsn
Targeted Allele Detail

Summary

• Symbol: Wt1^tm1Nhsn
• Name: WT1 transcription factor; targeted mutation 1, Naoki Hosen
• MGI ID: MGI:3721102
• Synonyms: WT1^GFP
• Gene: Wt1 Location: Chr2:104956874-105003959 bp, + strand Genetic Position: Chr2, 55.06 cM, cytoband E
• Alliance: Wt1^tm1Nhsn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:123972
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• The enhanced green fluorescent protein gene was fused in-frame to the ATG of the endogenous gene. (J:123972)

Expression

In Mice Carrying this Mutation:	32 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Wt1 Mutation: 34 strains or lines available

References

• Original: J:123972 Hosen N, et al., The Wilms' tumor gene WT1-GFP knock-in mouse reveals the dynamic regulation of WT1 expression in normal and leukemic hematopoiesis. Leukemia. 2007 Aug;21(8):1783-91
• All: 25 reference(s)