Or10a4^tm5(rtTA)Rax
Targeted Allele Detail

Summary

• Symbol: Or10a4^tm5(rtTA)Rax
• Name: olfactory receptor family 10 subfamily A member 4; targeted mutation 5, Richard Axel
• MGI ID: MGI:3721400
• Synonyms: P2-IRES-rtTA
• Gene: Or10a4 Location: Chr7:106696674-106697621 bp, + strand Genetic Position: Chr7, 56.1 cM, cytoband F2
• Alliance: Or10a4^tm5(rtTA)Rax page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:90981
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Transactivator)
• Mutation: Insertion
• Mutation details: An IRES fused tetracycline-dependent trasncriptional activator (rtTA) was inserted to create a bicistronic allele. rtTA is expressed in olfactory neurons expressing Olfr17. (J:90981)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Or10a4 Mutation: 22 strains or lines available

References

• Original: J:90981 Gogos JA, et al., Genetic ablation and restoration of the olfactory topographic map. Cell. 2000 Nov 10;103(4):609-20
• All: 2 reference(s)