Omp^tm1(tTA)Gogo
Targeted Allele Detail

Summary

• Symbol: Omp^tm1(tTA)Gogo
• Name: olfactory marker protein; targeted mutation 1, Joseph Gogos
• MGI ID: MGI:3721403
• Synonyms: OMP-IRES-tTA
• Gene: Omp Location: Chr7:97792566-97794654 bp, - strand Genetic Position: Chr7, 53.59 cM
• Alliance: Omp^tm1(tTA)Gogo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:124299
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Transactivator)
• Mutation: Insertion
• Mutation details: An IRES fused tetracycline-controlled transcriptional activator (tTA) to create a bicistronic allele was inserted into the 3' untranslated region of Omp. tTA is expressed in all Omp+ olfactory nerve cells. (J:124299)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Omp Mutation: 27 strains or lines available

References

• Original: J:124299 Yu CR, et al., Spontaneous neural activity is required for the establishment and maintenance of the olfactory sensory map. Neuron. 2004 May 27;42(4):553-66
• All: 30 reference(s)