Txnrd1^tm1Ees
Targeted Allele Detail

Summary

• Symbol: Txnrd1^tm1Ees
• Name: thioredoxin reductase 1; targeted mutation 1, Edward E Schmidt
• MGI ID: MGI:3722091
• Synonyms: Txnrd1^cond
• Gene: Txnrd1 Location: Chr10:82669785-82733546 bp, + strand Genetic Position: Chr10, 40.66 cM
• Alliance: Txnrd1^tm1Ees page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:124356
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• LoxP sites were inserted upstream of exon 1 and in intron 2. (J:124356)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Tumor Data

List all tumor models in MMHCdb carrying Txnrd1^tm1Ees

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Txnrd1 Mutation: 49 strains or lines available

References

• Original: J:124356 Bondareva AA, et al., Effects of thioredoxin reductase-1 deletion on embryogenesis and transcriptome. Free Radic Biol Med. 2007 Sep 15;43(6):911-23
• All: 8 reference(s)