Pebp1^{Gt(AQ0005)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Pebp1^{Gt(AQ0005)Wtsi}
• Name: phosphatidylethanolamine binding protein 1; gene trap AQ0005, Wellcome Trust Sanger Institute
• MGI ID: MGI:3722117
• Synonyms: Rkip1^{Gt(pGT01xrBetageo)1Jkl}
• Gene: Pebp1 Location: Chr5:117420716-117425629 bp, - strand Genetic Position: Chr5, 56.88 cM
• Alliance: Pebp1^{Gt(AQ0005)Wtsi} page

Mutation origin

• Mutant Cell Line: AQ0005
• Germline Transmission: Earliest citation of germline transmission: J:124490
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0lxr
• Mutation details: A gene trap vector containing a beta-geo inserted into intron 1 of the locus. Tail fibroblasts from homozygous mice had no endogenous gene expression as determined by RT-PCR and Western blots. Beta-gal expression was detected in the brains of homozygous mice. (J:124490)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  AQ0005	CL569585 ; (MGI Seq Detail)	5' RACE	multiple
  * GRCm39; (strand of gene trap mutagenesis)

Expression

In Mice Carrying this Mutation:

4 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pebp1 Mutation: 18 strains or lines available

References

• Original: J:124490 Theroux S, et al., Raf kinase inhibitory protein knockout mice: expression in the brain and olfaction deficit. Brain Res Bull. 2007 Mar 30;71(6):559-67
• All: 13 reference(s)