Ifna6^tm1Aki
Targeted Allele Detail

Summary

• Symbol: Ifna6^tm1Aki
• Name: interferon alpha 6; targeted mutation 1, Shizuo Akira
• MGI ID: MGI:3722118
• Synonyms: Ifna6^gfp, Ifna6gfp
• Gene: Ifna6 Location: Chr4:88745653-88746222 bp, + strand Genetic Position: Chr4, 42.03 cM
• Alliance: Ifna6^tm1Aki page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:124340
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: The entire open reading frame was replaced with a floxed neo-cassette and a fragment encoding EGFP. The neo was subsequently removed via transient cre expression. (J:124340)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ifna6 Mutation: 16 strains or lines available

References

• Original: J:124340 Kumagai Y, et al., Alveolar Macrophages Are the Primary Interferon-alpha Producer in Pulmonary Infection with RNA Viruses. Immunity. 2007 Aug;27(2):240-52
• All: 7 reference(s)