Trpc2^tm2Mom
Targeted Allele Detail

Summary

• Symbol: Trpc2^tm2Mom
• Name: transient receptor potential cation channel, subfamily C, member 2; targeted mutation 2, Peter Mombaerts
• MGI ID: MGI:3722352
• Synonyms: Trpc2-IRES-taumCherry
• Gene: Trpc2 Location: Chr7:101732323-101745603 bp, + strand Genetic Position: Chr7, 54.71 cM, cytoband F1
• Alliance: Trpc2^tm2Mom page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:218085
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: An IRES-taumCherry cassette, along with self-excising ACNF selection cassette, was inserted 32 base pairs downstream of the STOP codon of the endogenous coding sequence so that the taumCherry fusion protein is co-expressed to mark endogenous gene expression. (J:218085)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Trpc2 Mutation: 98 strains or lines available

References

• Original: J:218085 Omura M, et al., Trpc2-expressing sensory neurons in the mouse main olfactory epithelium of type B express the soluble guanylate cyclase Gucy1b2. Mol Cell Neurosci. 2015 Mar;65:114-24
• All: 5 reference(s)