Or55b10^tm4Mom
Targeted Allele Detail

Summary

• Symbol: Or55b10^tm4Mom
• Name: olfactory receptor family 55 subfamily B member 10; targeted mutation 4, Peter Mombaerts
• MGI ID: MGI:3722369
• Synonyms: deltaS50-YFP, venusYFP->S50
• Gene: Or55b10 Location: Chr7:102143030-102143980 bp, - strand Genetic Position: Chr7, 54.74 cM
• Alliance: Or55b10^tm4Mom page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:144169
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding sequence was replaced with venusYFP and clone deltaS50-101 was used to generate this allele. (J:144169)

Phenotypes

Key:

hm	homozygous	ht	heterozygous	tg	involves transgenes	√	phenotype observed
cn	conditional genotype	cx	complex: > 1 genome feature	ot	other: hemizygous, indeterminate,...	N	normal phenotype

Genotype/
Background:

	Allelic Composition	Genetic Background	Cell Line(s)
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ot1	Or55b10^tm4Mom/?	involves: 129P2/OlaHsd * C57BL/6J

Phenotypes:

Affected Systems	ot1
show or hide all annotated terms
nervous system	√
abnormal olfactory bulb development	√

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Or55b10 Mutation: 17 strains or lines available

References

• Original: J:144169 Bozza T, et al., Mapping of Class I and Class II Odorant Receptors to Glomerular Domains by Two Distinct Types of Olfactory Sensory Neurons in the Mouse. Neuron. 2009 Jan 29;61(2):220-33
• All: 3 reference(s)