Or2b4^tm5(cre)Mom
Targeted Allele Detail

Summary

• Symbol: Or2b4^tm5(cre)Mom
• Name: olfactory receptor family 2 subfamily B member 4; targeted mutation 5, Peter Mombaerts
• MGI ID: MGI:3722381
• Synonyms: Cre-SR1, deltaSR1-Cre
• Gene: Or2b4 Location: Chr17:38115960-38117081 bp, + strand Genetic Position: Chr17, 19.16 cM
• Alliance: Or2b4^tm5(cre)Mom page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:214042
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutations: Insertion, Intragenic deletion
• Or2b4^tm5(cre)Mom expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Or2b4 (MGI:2177507)

• Mutation details: The locus is replaced with a nuclear localized cre. The final allele lacks the self-excising neomycin resistance cassette. (J:214042)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Or2b4 (mouse) Summary of all recombinase alleles driven by Or2b4. Comparative matrix view of recombinase activities Alliance mouse Or2b4 gene page

Expression

In Mice Carrying this Mutation:

2 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Or2b4 Mutation: 22 strains or lines available

References

• Original: J:214042 Fuss SH, et al., Odorant receptor gene choice and axonal wiring in mice with deletion mutations in the odorant receptor gene SR1. Mol Cell Neurosci. 2013 Sep;56:212-24
• All: 1 reference(s)