Tg(Col2a1-Npr2*B2)25-4Gar
Transgene Detail

Summary

• Symbol: Tg(Col2a1-Npr2*B2)25-4Gar
• Name: transgene insertion 25-4, David L Garbers
• MGI ID: MGI:3722765
• Synonyms: GCB2-Tgm, Tg(Col2a1-Npr2)254Gar, Tg(Col2a1-Npr2)25-4Gar
• Transgene: Tg(Col2a1-Npr2*B2)25-4Gar Location: unknown
• Alliance: Tg(Col2a1-Npr2*B2)25-4Gar page

Transgene origin

• Strain of Origin: C57BL/6 and SJL

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Col2a1-Npr2*B2)25-4Gar expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Npr2 (MGI:97372)

• Mutation details: A transgenic B-geo expression construct incorporating the GC-B2 isoform of the mouse gene (expressed in growth-plate chondrocytes) driven by the mouse Col2a1 (procollagen, type II, alpha 1) promoter/enhancer was generated for microinjection. Lin 25-4 was developed. (J:94718)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:94718 Tamura N, et al., Critical roles of the guanylyl cyclase B receptor in endochondral ossification and development of female reproductive organs. Proc Natl Acad Sci U S A. 2004 Dec 7;101(49):17300-5
• All: 1 reference(s)