Cdk1^{Gt(P009F08)Bbd}
Gene trapped Allele Detail

Summary

• Symbol: Cdk1^{Gt(P009F08)Bbd}
• Name: cyclin dependent kinase 1; gene trap P009F08, Mariano Barbacid
• MGI ID: MGI:3722849
• Synonyms: Cdc2a^mut2
• Gene: Cdk1 Location: Chr10:69170976-69188742 bp, - strand Genetic Position: Chr10, 36.07 cM
• Alliance: Cdk1^{Gt(P009F08)Bbd} page

Mutation origin

• Mutant Cell Line: P009F08
• Germline Transmission: Earliest citation of germline transmission: J:124678
• Parent Cell Line: IDG3.2 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: FlipROSAbetageo
• Mutation details: The insertion of a gene trap vector containing a betageo cassette disrupted the locus 0.8 kb downstream of exon 1. (J:99313, J:124678)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  P009F08	CL303046 ; (MGI Seq Detail)	5' RACE	Chr10:69185925-69188722 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  25 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdk1 Mutation: 21 strains or lines available

References

• Original: J:124678 Santamaria D, et al., Cdk1 is sufficient to drive the mammalian cell cycle. Nature. 2007 Aug 16;448(7155):811-5
• All: 4 reference(s)