Cdk1^{Gt(pGT1-3)1Bbd}
Gene trapped Allele Detail

Summary

• Symbol: Cdk1^{Gt(pGT1-3)1Bbd}
• Name: cyclin dependent kinase 1; gene trap 1, Mariano Barbacid
• MGI ID: MGI:3722851
• Synonyms: Cdc2a^mut1
• Gene: Cdk1 Location: Chr10:69170976-69188742 bp, - strand Genetic Position: Chr10, 36.07 cM
• Alliance: Cdk1^{Gt(pGT1-3)1Bbd} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:124678
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The insertion of a gene trap vector containing a betageo cassette disrupted the locus 2 kb downstream of exon 1. (J:71817, J:124678)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdk1 Mutation: 21 strains or lines available

References

• Original: J:124678 Santamaria D, et al., Cdk1 is sufficient to drive the mammalian cell cycle. Nature. 2007 Aug 16;448(7155):811-5
• All: 3 reference(s)