Pik3cgtm2Ehi
Targeted Allele Detail
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Symbol: |
Pik3cgtm2Ehi |
Name: |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; targeted mutation 2, Emilio Hirsch |
MGI ID: |
MGI:3722941 |
Synonyms: |
p110gammaCAAX, PikgammaCX |
Gene: |
Pik3cg Location: Chr12:32223472-32258658 bp, - strand Genetic Position: Chr12, 13.74 cM, cytoband B
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Alliance: |
Pik3cgtm2Ehi page
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Spontaneous skin lesions in Pik3cgtm2Ehi/Pik3cgtm2Ehi mice
Show the 1 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:124856
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted |
Mutation: |
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Insertion
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Mutation details: The locus encoding the catalytic subunit was replaced with a chimeric minigene containing a mutant form of the human cDNA in which the CAAX motif was added at its 5' end.
(J:124856)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Pik3cg Mutation: |
59 strains or lines available
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Original: |
J:124856 Costa C, et al., Negative feedback regulation of Rac in leukocytes from mice expressing a constitutively active phosphatidylinositol 3-kinase {gamma}. Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14354-9 |
All: |
3 reference(s) |
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