Pax9^tm1.1Hpt
Targeted Allele Detail

Summary

• Symbol: Pax9^tm1.1Hpt
• Name: paired box 9; targeted mutation 1.1, Heiko Peters
• MGI ID: MGI:3723638
• Synonyms: Pax9^flox
• Gene: Pax9 Location: Chr12:56738552-56759607 bp, + strand Genetic Position: Chr12, 24.53 cM
• Alliance: Pax9^tm1.1Hpt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:125026
• Parent Cell Line: TBV2 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: FLPe-recombnation was used to remove the neo cassette leaving exons 1 and 2 floxed. Removal of the neo cassette was confirmed by Southern blot. (J:125026)

Expression

In Structures Affected by this Mutation:

12 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Pax9^tm1.1Hpt

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pax9 Mutation: 17 strains or lines available

References

• Original: J:125026 Kist R, et al., Derivation of a mouse model for conditional inactivation of Pax9. Genesis. 2007 Jul;45(7):460-4
• All: 6 reference(s)