Slc27a5^tm1Asta
Targeted Allele Detail

Summary

• Symbol: Slc27a5^tm1Asta
• Name: solute carrier family 27 (fatty acid transporter), member 5; targeted mutation 1, Andreas Stahl
• MGI ID: MGI:3757682
• Gene: Slc27a5 Location: Chr7:12722273-12732119 bp, - strand Genetic Position: Chr7, 7.71 cM
• Alliance: Slc27a5^tm1Asta page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:124917
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with a promoterless nuclear localization signal-tagged lacZ/PGK-neo cassette. The absence of protein product was confirmed by western blot analysis on liver lysates. (J:124917)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc27a5 Mutation: 31 strains or lines available

References

• Original: J:124917 Doege H, et al., Targeted deletion of FATP5 reveals multiple functions in liver metabolism: alterations in hepatic lipid homeostasis. Gastroenterology. 2006 Apr;130(4):1245-58
• All: 4 reference(s)