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Il20rbtm1Dnax
Targeted Allele Detail
Summary
Symbol: Il20rbtm1Dnax
Name: interleukin 20 receptor beta; targeted mutation 1, DNAX Research Institute of Cellular and Molecular Biology
MGI ID: MGI:3757693
Synonyms: Il20-R2-, IL20R2tm1Dnax
Gene: Il20rb  Location: Chr9:100339772-100368526 bp, - strand  Genetic Position: Chr9, 52.66 cM
Alliance: Il20rbtm1Dnax page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:124591
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe transcription start site and leader sequence from exon 1 and a portion of intron 1 were replaced with a LacZ-neo cassette. (J:124591)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il20rb Mutation:  31 strains or lines available
References
Original:  J:124591 Chan JR, et al., IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis. J Exp Med. 2006 Nov 27;203(12):2577-87
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory